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Достижения

Достижения ЦКП

На площадке ЦКП проводятся совместные научные исследования в рамках НИР кафедр и структурных подразделений Университета по исследованию новых лекарственных средств.

За период существования сотрудниками ЦКП выполнена работа по доклиническому изучению 4 новых ЛС в рамках Государственных контрактов.

Проводится работа в рамках заключенных договоров для внешних пользователей по разработке аналитических методик контроля качества и их валидации, изучению специфической фармакологической активности и токсичности, подбору дозы, разработке оптимальной технологии как новых ЛС так и воспроизведенных.

Сотрудники лаборатории являются авторами и соавторами более 180 научных публикаций, в т.ч. патентов.

Достижения

Основные достижения

  • Достижения центра

•    Организация, проведение и выполнение научно-исследовательских, научно-образовательных работ в рамках государственных научно-исследовательских программ, Федеральных целевых программ, программ Министерств Российской Федерации и других заказчиков в соответствии с профилем деятельности ЦФТ.
•    Развитие инновационной деятельности с целью создания лекарственных препаратов, оказания наукоёмких услуг, ориентированных на потребности фармацевтических предприятий.
•    Коммерциализация результатов научно-исследовательской, научно-образовательной и инновационной деятельности в соответствии с законодательством РФ и Уставом СПХФУ.
•    Проведение научных мероприятий (семинаров, конференций, круглых столов, симпозиумов и пр.).
•    Участие в международных программах и проектах.
•    Проведение работ по защите интеллектуальной собственности (патенты, полезные модели,  «ноу-хау» и др.), систематическое накопление и применение «ноу-хау» в деятельности ЦФТ.
•    Участие в реализации образовательных программ высшего и послевузовского профессионального образования на основе государственных образовательных стандартов, переподготовка и повышение квалификации научных и научно-педагогических работников.

  • Научные исследования и разработки

•    Твёрдых лекарственных форм (таблетки, гранулы, твёрдые желатиновые капсулы, лиофилизаты, пеллеты, плёнки, суппозитории);
•    Мягких лекарственных форм (мази, кремы, гели, линименты);
•    Жидких лекарственных форм (растворы, суспензии, эмульсии, настойки, экстракты, сиропы, спреи);
•    Лекарственных форм с улучшенной биологической доступностью путём улучшения растворимости лекарственных средств, создания твёрдых дисперсных систем, микрокапсул, пеллет;
•    Лекарственных форм с модифицированным высвобождением;

  • Основные компетенции

•    разработка и обоснование оптимального состава лекарственной формы;
•    биофармацевтическая оценка лекарственных средств в условиях in vitro (в т.ч. моделирование условий ЖКТ in vitro, разработка методик количественного определения лекарственного вещества в среде растворения);
•    выбор и обоснование технологических режимов, показателей качества готового лекарственного средства, разработка методик контроля качества лекарственных форм;
•    изучение стабильности разработанного лекарственного средства методом «ускоренного старения» и в естественных условиях;
•    разработка нормативной и технологической документации (спецификация, лабораторный регламент, технологическая инструкция) на готовый лекарственный препарат;
•    составление отчёта о научно-исследовательской работе в соответствии с ГОСТ 7.32-2001.

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